The Annunciation
The Angel Gabriel announces the future birth of Christ. The hand of God sends a dove, a symbol of the Holy Spirit, in a spiral towards Mary's womb. Gold rays emanate from a hole in her dress. Various symbols, such as lilies and the walled garden, allude to her virginity.
Like its companion panel, the Seven Saints, displayed nearby, this came from Palazzo Medici in Florence and was probably commissioned by the Medici family. On the parapet is the Medici device of three feathers within a ring.